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That single distinction, the receptor each one targets, explains almost everything else about how these three peptides behave in published studies

When arriving at the tumour site, the de-shielding of PEG corona triggered by tumour acidity leads to the exposure of ECM targeting peptide and anchoring on the ECM, allowing T ECM -NS to continuously scavenge extracellular ROS

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This copper-peptide bond produces the compound's biological effects, triggering gene expression changes that promote anti-aging and tissue repair responses